Catalytic antibodies and a method of producing same

A growth factor precursor comprising an antigen capable of interacting with a B cell bound catalytic antibody, wherein said antigen is fused to a B cell surface molecule binding portion such that upon cleavage of the antigen mitogenesis of the B cell comprising the remainder of the precursor is indu...

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Bibliographische Detailangaben
Hauptverfasser:	KOENTGEN, FRANK, TREUTLEIN, HERBERT RUDOLF, SUESS, GABRIELE, TARLINTON, DAVID MATTHEW
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A growth factor precursor comprising an antigen capable of interacting with a B cell bound catalytic antibody, wherein said antigen is fused to a B cell surface molecule binding portion such that upon cleavage of the antigen mitogenesis of the B cell comprising the remainder of the precursor is induced thereby producing more of the catalytic antibody, is used in the manufacture of a medicament for the treatment of a condition mediated by the antigen or a gent comprising the antigen. (62) Divided out of 515603