Stabilised radiopharmaceutical composition comprising an amino-substituted aromatic carboxylic acid and a diphosphonic acid as stabilisers

A stabiliser for radiopharmaceuticals that inhibits impurities from being produced by two kinds of decomposition mechanisms and exhibits such an effect that the shelf life of a radiopharmaceutical after its preparation is prolonged as compared with conventional ones is disclosed. The stabilised radi...

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Hauptverfasser: HOMMA, KOICHI, STOREY, ANTHONY EAMON, MINOSAKO, YOSHIHITO, HANAOKA, KOICHI, BRAUERS, GEORG, SHIRAKAMI,YOSHIFUMI
Format: Patent
Sprache:eng
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Zusammenfassung:A stabiliser for radiopharmaceuticals that inhibits impurities from being produced by two kinds of decomposition mechanisms and exhibits such an effect that the shelf life of a radiopharmaceutical after its preparation is prolonged as compared with conventional ones is disclosed. The stabilised radiopharmaceutical composition comprises a combination of an amino-substituted aromatic carboxylic acid or its salt, ester or amide in combination with a diphosphonic acid or its salt.