Methods of producing a terminally sterilized topical patch preparation

A method of producing a terminally sterilized topical patch preparation comprising: - exposing a topical patch preparation to electron beam radiation for a period of time sufficient to terminally sterilize said topical patch preparation, - producing a terminally sterilized topical patch preparation....

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Bibliographische Detailangaben
Hauptverfasser: CALDWELL, LARRY, DUONG, TU XUAN, SHUDO, JUTARO
Format: Patent
Sprache:eng
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Zusammenfassung:A method of producing a terminally sterilized topical patch preparation comprising: - exposing a topical patch preparation to electron beam radiation for a period of time sufficient to terminally sterilize said topical patch preparation, - producing a terminally sterilized topical patch preparation. The topical patch may be packaged and sealed in an aluminum layer. The topical patch may be an adhesive gel composition comprising: - an active ingredient, such as a local anesthetic. - a water soluble polymer gel, - water, and - a water holding agent. Also a kit for a transdermal patch as described above which includes instructions for use is disclosed.