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An isolated antibody having specific for a target structure displayed on the surface of human gastrointestinal epithelial tumour cells, with the binding domain complementarity determining region (CDR) sequences in the light chain comprising amino acids 23-33 (CDR1), 49- 55 (CDR2), 88-98 (CDR3) of SE...

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Hauptverfasser: KARLSTROM, PIA J, OHLSSON, LENNART G, NILSON, BO H K, ORDSSON, M JESPER, KEARNEY, PHILIP P, BRODIN, THOMAS
Format: Patent
Sprache:eng
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Zusammenfassung:An isolated antibody having specific for a target structure displayed on the surface of human gastrointestinal epithelial tumour cells, with the binding domain complementarity determining region (CDR) sequences in the light chain comprising amino acids 23-33 (CDR1), 49- 55 (CDR2), 88-98 (CDR3) of SEQ ID NO:2, and the binding domain CDR of the heavy chain comprising amino acids 158- 162 (CDR1), 177-193 (CDR2), 226-238 (CDR3) of SEQ ID NO:2.