Aromatic sulfone hydroxamic acid metalloprotease inhibitor

The use of a compound of formula B in the preparation of a pharmaceutical composition for treating a condition associated with pathological matrix metalloprotease (MMP) activity, wherein X, Y and Z form a carbocycle or heterocycle containing N, S, or O atoms.

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Bibliographische Detailangaben
Hauptverfasser:	TOLLEFSON, MICHAEL B, FOBIAN,YVETTE M, FRESKOS, JOHN N, GETMAN, DANIEL P, RICO, JOSEPH G, DECRESCENZO, GARY A, LI, MADELEINE HUI, BEDELL, LOUIS J, MCDONALD, JOSEPH J, CARROLL, JEFFREY N, HOCKERMAN, SUSAN L, HOWARD, SUSAN C, BOEHM, TERRI L, STEHLE, NATHAN W, VERNIER,WILLIAM R, BECKER, DANIEL P, VILLAMIL, CLARA I, MISCHKE, DEBORAH A, BARTA, THOMAS E, KOLODZIEJ,STEPHEN A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The use of a compound of formula B in the preparation of a pharmaceutical composition for treating a condition associated with pathological matrix metalloprotease (MMP) activity, wherein X, Y and Z form a carbocycle or heterocycle containing N, S, or O atoms.