Polypeptides derived from JNK3

An isolated derivative of JNK3 that contains a deletion in the N-terminal region corresponding to the 1-38 fragment of the JNKAlpha1 or JNKAlpha2 isoform, the derivative having sequence ID no.23 or 25, or variants of such sequences in which one amino acid is modified. Also disclosed is an isolated d...

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Hauptverfasser: DESANLIS, FRANCINE, MAURY, ISABELLE, ZHOU-LIU, QING, FOURNIER, ALAIN
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creator DESANLIS, FRANCINE
MAURY, ISABELLE
ZHOU-LIU, QING
FOURNIER, ALAIN
description An isolated derivative of JNK3 that contains a deletion in the N-terminal region corresponding to the 1-38 fragment of the JNKAlpha1 or JNKAlpha2 isoform, the derivative having sequence ID no.23 or 25, or variants of such sequences in which one amino acid is modified. Also disclosed is an isolated derivative of JNK3 that contains a deletion in the C-terminal region from amino acids 139 onwards. Further is the use of ligands that bind to such derivatives in the preparation of medicaments to treat diseases involving neuronal degeneration.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Polypeptides derived from JNK3
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