Benzoxazole substituted piperazine and piperidine derivatives useful for treating central nervous disorders, depression and anxiety

Piperazine and piperidine derivatives of formula (I), their salts and pharmaceutical compositions, where: S1 is hydrogen, halogen, alkyl (1-3C), CN, CF3, OCF3, SCF3, alkoxy (1-3C), amino or mono- or dialkyl (1-3C) substituted amino, or hydroxy; X represents NR3, S, CH2, O, SO or SO2, where R3 is H or alkyl (1-3C);. Z represents =C or -N; R1 and R2 independently represent H or alkyl (1-3C), or R1 and R2 together can form a bridge of 2 or 3 C-atoms; R4 is hydrogen or alkyl (1-3C); Q is methyl, ethyl, ethyl substituted with one or more fluorine atoms, cyclopropyl - methyl, optionally substituted with one or more fluorine atoms. These compounds have both partial dopamine D2-receptor agonism and partial serotonin 5-HT1A-receptor agonism mediated activities.