Continuous process for purifying a solution of an ampicillin pro-drug ester
A process for purifying a solution of an ampicillin pro-drug of formula (I) comprises a step wherein a crude solution of the ampicillin pro-drug is subjected to an evaporation which is controlled by the evaporation rate of the organic solvent such that a continuous operation is accomplished for the...
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| Sprache: | eng |
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| Zusammenfassung: | A process for purifying a solution of an ampicillin pro-drug of formula (I) comprises a step wherein a crude solution of the ampicillin pro-drug is subjected to an evaporation which is controlled by the evaporation rate of the organic solvent such that a continuous operation is accomplished for the crystallization of the desired purified pro-drug ester. The crystallization is preferably preceded by an aqueous phase extraction and/or an organic phase extraction, both preferably also being performed continuously. |
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