Benzenesulfonamide inhibitors of phosphodiesterase-IV for treating inflammation and TNF associated diseases
A method of inhibiting PDE-IV or TNF comprising contacting a cell with a compound of the formula shown. The pharmaceutical composition is suitable for the treatment of inflammatory or autoimmune diseases. Wherein; R1 and R2 represents C1-4alkyl or C3-10cycloalkyl; R3 and R4 independently represents...
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