Contrast media comprising superparamagnetic particles in an organic coating

The application relates to MR contrast media containing composite nanoparticles, comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence...

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Bibliographische Detailangaben
Hauptverfasser:	FUJII, DENNIS KIYOSHI, GUNTHER, WOLFGANG, BEEBER, MARSHALL, MCINTIRE, GREGORY LYNN, DESAI, VINAY, YUAN, BARBARA, SNOW, ROBERT ALAN, WEEKLEY, BRIAN, STEVENS, JACK, GACEK, MICHEL, KELLAR, KENNETH, WELLONS, JENNIFER, NAEVESTAD, ANNE, ENGELL, TORGRIM, SINGH, JASBIR, FAHLVIK, ANNE KJERSTI, NA, GEORGE, BLACK, CHRISTOPHER, LADD, DAVID LEE, BACON, EDWARD RICHARD
Format:	Patent
Sprache:	eng
Schlagworte:	AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSESC01D OR C01F GENERAL PROCESSES OF COMPOUNDING HUMAN NECESSITIES HYGIENE INORGANIC CHEMISTRY MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP WORKING-UP
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Beschreibung
Zusammenfassung:	The application relates to MR contrast media containing composite nanoparticles, comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence. The application relates to MR contrast media containing composite nanoparticles, comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence.