Quinoline derivatives having neurokinin antagonist activity, preparation and use thereof
A compound, or a solvate or a salt thereof, of the above formula, wherein: Ar is an optionally substituted aryl or a C5-7 cycloalkdienyl group, or an optionally substituted single or fused ring aromatic heterocyclic group, preferably phenyl; R, R1, R2 and R3 are as defined in the description. Also c...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A compound, or a solvate or a salt thereof, of the above formula, wherein: Ar is an optionally substituted aryl or a C5-7 cycloalkdienyl group, or an optionally substituted single or fused ring aromatic heterocyclic group, preferably phenyl; R, R1, R2 and R3 are as defined in the description. Also claimed is a process for the preparation of such a compound and a pharmaceutical composition containing such a compound in the manufacture of a medicament for the treatment of respiratory, neurogenic inflammation, allergies and cutaneous diseases. Other conditions are as defined in the description.
A compound, or a solvate or a salt thereof, of the above formula, wherein: Ar is an optionally substituted aryl or a C5-7 cycloalkdienyl group, or an optionally substituted single or fused ring aromatic heterocyclic group, preferably phenyl; R, R1, R2 and R3 are as defined in the description. Also claimed is a process for the preparation of such a compound and a pharmaceutical composition containing such a compound in the manufacture of a medicament for the treatment of respiratory, neurogenic inflammation, allergies and cutaneous diseases. Other conditions are as defined in the description. |
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