LIPID CLEAVAGE ENZYME COMPLEX AND USE IN DIAGNOSTIC TESTING TO IDENTIFY COMPOUNDS THAT ACT AS A LIGAND OR SUBSTRATE OF THE COMPLEX

A membranous enzyme not yet described in the state-of-the-art can be extracted from cellular membrane fractions of blood leukocytes or monocytes/macrophages. Also disclosed is the use of substrates of this enzyme to prepare medicaments that contain these substrates as pharmaceutical active substance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OPTIZ, HANS-GEORG, ZILCH, HARALD, HERRMANN, DIETER
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A membranous enzyme not yet described in the state-of-the-art can be extracted from cellular membrane fractions of blood leukocytes or monocytes/macrophages. Also disclosed is the use of substrates of this enzyme to prepare medicaments that contain these substrates as pharmaceutical active substance. These medicaments are useful to direct pharmacologically active substances to target cells and to enrich target cells with said substances. Also disclosed are in-vitro research systems containing this enzyme used to detect other substrates of this enzyme.