CRYSTAL FORM OF A 7-(AZABICYCLOHEXYL)-NAPHTHYRIDINE-3-CARBOXYLIC ACID SALT; MEDICAMENTS

New crystal form, (I'), of 7-([1~a, 5~a, 6~a]-6-amino-3-azabicyclo [3.1.0] hex-3-yl)-6- fluoro-1-(2,4-difluorophenyl)- 1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acid, methanesulphonic acid salt (I), is characterised by the following major peaks in its X-ray powder diffraction pattern: P...

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Hauptverfasser:	MORRIS, THOMAS A, JOHNSON, PHILLIP J, HENDRICKSON, ROBERT L, NORRIS, TIMOTHY, HANDANYAN, LYNNE A
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	New crystal form, (I'), of 7-([1~a, 5~a, 6~a]-6-amino-3-azabicyclo [3.1.0] hex-3-yl)-6- fluoro-1-(2,4-difluorophenyl)- 1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acid, methanesulphonic acid salt (I), is characterised by the following major peaks in its X-ray powder diffraction pattern: Peak number; 2~h( deg )Cu; d space: (1; 4.5; 19.5); (2; 7.7; 11.5); (3; 9.1; 9.7); (4; 13.6; 6.5); (5; 15.0; 5.9); (6; 18.2; 4.9); (7; 18.6; 4.8); (8; 22.8; 3.9).