RAPIDLY DISSOLVING ORAL DOSAGE FORM CONTAINING A PARTICULATE SUPPORT MATRIX

RAPIDLY DISSOLVING ORAL DOSAGE FORM CONTAINING A PARTICULATE SUPPORT MATRIX

The present invention concerns a particulate support matrix, a solid dosage form made therefrom, and processes for making such support matrices and dosage forms, which desintegrate or dissolve in a matter of just a few seconds once placed into the oral cavity. First, a porous particulate powder whic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ALLEN, LLOYD V, DAVIES, JOHN DESMOND, WANG, BINGNAN
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT THEREOF
MEDICAL OR VETERINARY SCIENCE
NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS
NANOTECHNOLOGY
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TRANSPORTING
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Beschreibung
Zusammenfassung:The present invention concerns a particulate support matrix, a solid dosage form made therefrom, and processes for making such support matrices and dosage forms, which desintegrate or dissolve in a matter of just a few seconds once placed into the oral cavity. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.