BONE SUBSTITUTE COMPOSITIONS: HYDROXYAPATITE AND/OR TRICALCIUM PHOSPHATE AND 7-ISOPROPOXYISOFLAVONE

BONE SUBSTITUTE COMPOSITIONS: HYDROXYAPATITE AND/OR TRICALCIUM PHOSPHATE AND 7-ISOPROPOXYISOFLAVONE

The invention relates to the use of Ipriflavone (7-isopropoxyisoflavone) and combinations thereof with porous hydroxylapatite and/or tricalcium phosphate for the substitution of bone defects having pathologically developed or being artificially established, as well as to compositions containing thes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LEVAI, FERENC, KLENK, GUSZTAV, HORVATH, TIBOR, ENGLOVSZKY, ERZSEBET, PREZMECKY, LASZLO, MISZKIEWICZ, LASZLO, SZEKACS, GABOR, VITANYI, MAGDOLNA
Format: Patent
Sprache:eng
Schlagworte:
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to the use of Ipriflavone (7-isopropoxyisoflavone) and combinations thereof with porous hydroxylapatite and/or tricalcium phosphate for the substitution of bone defects having pathologically developed or being artificially established, as well as to compositions containing these active ingredients and their preparation. In the combinations of the invention, the mass ratio A/B of porous hydroxylapatite and/or tricalcium phosphate (A) to Ipriflavone (B) is preferably 1:9 to 9:1 and most preferably 1:1. The components are preferably present in the form of discrete granules. Preferably, the Ipriflavone is applied onto the surface of the porous hydroxylapatite and/or tricalcium phosphate. The compositions of the invention lead to an accelerated bone formation.