POLYSTYRENE POLYMERS AND USE AS PHARMACEUTICAL COMPOSITIONS

Polymers of structure (I): in which, R is a saturated or unsaturated C6 to C20 alkyl group; R and R are the same or different and are each C1-4alkyl; X is a physiologically acceptable counter ion; a, b and c are numbers which indicate the relative molar percentages of the units present in a random d...

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Hauptverfasser: HICKEY, DEIRDRE MARY B, JAXAAMIEC, ALBERT A
Format: Patent
Sprache:eng
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Zusammenfassung:Polymers of structure (I): in which, R is a saturated or unsaturated C6 to C20 alkyl group; R and R are the same or different and are each C1-4alkyl; X is a physiologically acceptable counter ion; a, b and c are numbers which indicate the relative molar percentages of the units present in a random distribution in said polymer, (b) being from about 0.5 to about 10 molar percent, and (c) being from about 30 to about 99 molar percent; and n is a number indicating the number of repeating units in said polymer, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy for the lowering of serum cholesterol levels in humans.