1-ACYL- (AND 1-SULPHONYL-) 3-(4-(2-PYRIMIDINYL) -1-PIPERAZINYL) PROPANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

1-ACYL- (AND 1-SULPHONYL-) 3-(4-(2-PYRIMIDINYL) -1-PIPERAZINYL) PROPANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

1-(Heterocyclcarbonyl)- 3-(4-(2-pyrimidinyl)-1-piperazinyl) propanes of formula (I) and 1-(heterocyclylsulphonyl) -3- (4-(2-pyrimidinyl) -1-piperazinyl) propanes of formula (II) and pharmaceutically acceptable acid addn. salts are new. - R = heterocyclic gp. of formulae (a) - (n); and R1 = heterocyc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: WELCH, WILLARD MCKOWAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:1-(Heterocyclcarbonyl)- 3-(4-(2-pyrimidinyl)-1-piperazinyl) propanes of formula (I) and 1-(heterocyclylsulphonyl) -3- (4-(2-pyrimidinyl) -1-piperazinyl) propanes of formula (II) and pharmaceutically acceptable acid addn. salts are new. - R = heterocyclic gp. of formulae (a) - (n); and R1 = heterocyclic gp. of formulae (b), (c), (d) etc. (1) R = (c), etc.; and (2) R1 = (b) etc. - Prepn. is described.