PREPARATION OF RANITIDINE AND NIZATIDINE

PREPARATION OF RANITIDINE AND NIZATIDINE

The novel process for the preparation of the nitroethene derivatives ranitidine and nizatidine proceeds via novel intermediates and makes it possible to prepare the compounds mentioned in higher purity. A further advantage is that, in contrast to the known processes, no methane thiol is liberated, w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SCHICKANEDER, H, MORSDORF, P, AHRENS, K H
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The novel process for the preparation of the nitroethene derivatives ranitidine and nizatidine proceeds via novel intermediates and makes it possible to prepare the compounds mentioned in higher purity. A further advantage is that, in contrast to the known processes, no methane thiol is liberated, which is highly toxic and malodorous.