RECOMBINANT PRODUCTION OF 2,5-DIKETOGLUCONIC ACID REDUCTASE

A protein having 2,5-diketogluconic acid (2,5-DKG) reductase activity is produced by recombinant host cells. This can be used to convert 2,5-DKG stereoselectively into 2-keto-L-gluonic acid (2-KLG) which is a useful intermediate in the production of ascorbic acid (vitamin C).

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Bibliographische Detailangaben
Hauptverfasser: LAZARUS, ROBERT ALAN, ESTELL, DAVID AARON, RASTETTER, WILLIAM HARRY, MILLER, JEFFREY VEACH, LIGHT, DAVID RICHARD
Format: Patent
Sprache:eng
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Zusammenfassung:A protein having 2,5-diketogluconic acid (2,5-DKG) reductase activity is produced by recombinant host cells. This can be used to convert 2,5-DKG stereoselectively into 2-keto-L-gluonic acid (2-KLG) which is a useful intermediate in the production of ascorbic acid (vitamin C).