PROCESS FOR THE PREPARATION OF HALOGENATED HYDROXYNICOTINIC ACID
A process for the preparation of 5-halo-2-hydroxynicotinic acids having the formula wherein X is chlorine or bromine; Y and Z are selected from hydrogen, loweralkyl, loweralkoxy, chlorine, bromine, iodine or fluorine, is described which comprises halogenating the corresponding 2-hydroxynicotinic aci...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A process for the preparation of 5-halo-2-hydroxynicotinic acids having the formula wherein X is chlorine or bromine; Y and Z are selected from hydrogen, loweralkyl, loweralkoxy, chlorine, bromine, iodine or fluorine, is described which comprises halogenating the corresponding 2-hydroxynicotinic acid with hypohalous acid in a concentrated halogen acid or with a alkali-metal hypohalite in aqueous or aqueous basic solution. |
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