AVERMECTIN DERIVATIVES

Macrolides having the formula: in which R1, R2, R3 and the 22,23-linkage have the following values: A: R1 = H, R2 = OH, R3 = CH3, 22,23-single bond B: R1 = H, R2 = OH, R3 = CH3, 22,23-double bond C: R1 = OH, R2 = H, R3 = H, 22,23-double bond are isolated from the fermentation broth, using avermectin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	WHITE, R F, GOEGELMAN, R T, INAMINE, E S
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FODDER FOODS OR FOODSTUFFS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Macrolides having the formula: in which R1, R2, R3 and the 22,23-linkage have the following values: A: R1 = H, R2 = OH, R3 = CH3, 22,23-single bond B: R1 = H, R2 = OH, R3 = CH3, 22,23-double bond C: R1 = OH, R2 = H, R3 = H, 22,23-double bond are isolated from the fermentation broth, using avermectin Bla, avermectin Blb or 22,23-dihydro avermectin Bla as a substrate, of Nocardia autotrophica ATCC 35203. The compounds are highly potent antiparasitic, insecticidal, and anthelmintic agents and can be made into compositions for such uses.