(4,2,0)BICYCLOOCTANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

Compounds useful in treating cardiovascular disorders' such as thrombosis, hypertension, and atherosclerosis are compounds depicted in formulas (1), (2), and (3):wherein:n is 2 or 3;R1 is CH20H, CHO, CO2R or CO2H;R2 is hydrogen or methyl; andR3 is linear or branched alkyl having 5-10 carbon ato...

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Bibliographische Detailangaben
Hauptverfasser:	WILLIS, A L, O'YANG, C, KLUGE, A F
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY ELECTRIC COMMUNICATION TECHNIQUE ELECTRICITY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PICTORIAL COMMUNICATION, e.g. TELEVISION PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds useful in treating cardiovascular disorders' such as thrombosis, hypertension, and atherosclerosis are compounds depicted in formulas (1), (2), and (3):wherein:n is 2 or 3;R1 is CH20H, CHO, CO2R or CO2H;R2 is hydrogen or methyl; andR3 is linear or branched alkyl having 5-10 carbon atoms,optionally substituted with lower alkyl, lower alkoxy, trifluoromethyl, or halogen,in whicha is 0, 1 or 2;b is 3-7;m is 0, 1 or 2; andorin which R4 is independently hydrogenor lower alkyl having 1-6 carbon atoms;and the pharmaceutically acceptable, non-toxic salts and esters thereof.