UREA DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

Novel aminoalkyl substituted urea derivatives of the formula: wherein X and Y are the same or different and are selected from the group consisting of a phenyl group, each of said phenyl groups being optionally substituted with one or two groups selected from halogen, CF3, OH, or alkoxy (1-4 C-atoms); and R and R are the same or different, and are each selected from the group consisting of lower alkyk groups having from one to four carbon atoms inclusive, or they form together with the nitrogen atom a saturated five- or six-membered heterocyclic ring; R anmd R are each selected from hydrogen, lower alkyl or alkenyl groups with from 1-6 carbon atoms inclusive, cyclopentyl or cyclohexyl; and n is 0 or 1, as well as pharmaceutically acceptable acid addition salts thereof, and enantiomers, are described as having pronounced anti-neoplastic activity against various tumors. A method for the preparation of the compounds of Formula I is described, as well as pharmaceutical compositions containing a compound of Formula I as an active ingredient.