A-21978C DERIVATIVES

An improved process is provided for producing A-21978C cyclic peptide derivatives having a C2-C14 alkonoyl side chain which comprises feeding a C2-C14 alkanoic acid, or an ester or salt thereof, to the A-21978C-producing culture during the production stages of the fermentation. In addition, a new pr...

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Hauptverfasser: HUBER, F.M, GODFREY, D.W, HUBER, M.L.B, FORD, L.M, EATON, T.E, PIEPER, R.L, ZMIJEWSKI, M.J, TRETZ, A.J
Format: Patent
Sprache:eng
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Zusammenfassung:An improved process is provided for producing A-21978C cyclic peptide derivatives having a C2-C14 alkonoyl side chain which comprises feeding a C2-C14 alkanoic acid, or an ester or salt thereof, to the A-21978C-producing culture during the production stages of the fermentation. In addition, a new process is provided for producing the A-21978C antibiotics which comprises cultivating under aerobic conditions a new strain of microorganism.