CERTAIN 1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUORO-4-OXO-1,8-NAPHTHYRIDINE (AND QUINOLINE)-3-CARBOXYLIC ACID DERIVATIVES AND ANTIBACTERIAL COMPOSITIONS CONTAINING SUCH

Compound of formula where X is CH, CCl, CF, C-OH, CO-alkyl having from one to three carbons, C-NH-alkyl having from one to three carbons, or N; Y is H, F, Cl or Br; R2 is alkyl having from one to four carbon atoms, vinyl, haloalkyl, or hydroxyalkyl having from two to four carbon atoms or cycloalkyl...

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Bibliographische Detailangaben
Hauptverfasser: MICH, T.F, NICHOLS, J.B, DOMAGALA, J.M, CULBERTSON, T.P
Format: Patent
Sprache:eng
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Zusammenfassung:Compound of formula where X is CH, CCl, CF, C-OH, CO-alkyl having from one to three carbons, C-NH-alkyl having from one to three carbons, or N; Y is H, F, Cl or Br; R2 is alkyl having from one to four carbon atoms, vinyl, haloalkyl, or hydroxyalkyl having from two to four carbon atoms or cycloalkyl having three to six carbon atoms. Also described are methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the manufacture of the compounds. The compounds are useful as antibacterial agents.