N-ALKYL-(3 OR 4)-PIPERIDINYL BENZOATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

N-ALKYL-(3 OR 4)-PIPERIDINYL BENZOATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

Migraine is treated with an N-alkyl-(3 or 4)-piperidinyl benzoate compound of general Formula I:- wherein the benzoyloxy group is at the 3 or 4 position of the piperidine ring: n is 0, or an integer from 1 to 5; R1 represents C1-C4 alkyl; and each R2 represents C1-C4 alkyl, C1-C4 alkoxy, or halogen,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GITTOS, M.W, FOZARD, J.R
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Migraine is treated with an N-alkyl-(3 or 4)-piperidinyl benzoate compound of general Formula I:- wherein the benzoyloxy group is at the 3 or 4 position of the piperidine ring: n is 0, or an integer from 1 to 5; R1 represents C1-C4 alkyl; and each R2 represents C1-C4 alkyl, C1-C4 alkoxy, or halogen, provided that, when n is 2, the groups represented by R2 can be either the same or different, and, when n is 3, 4, or 5, the groups represented by R2 must be the same, or a pharmaceutically acceptable salt thereof.