4-ALKYLTHIOPHENYLETHANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH

4-ALKYLTHIOPHENYLETHANOLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH

4-alkyl-thiophenyl-ethanolamines are disclosed, which are compounds having a therapeutical activity against blood-platelet aggregation, and against lipemia and improving the cerebral circulation, said ethanolamines having the general formula: wherein R and R1 are alkyl substituents and R2 is a subst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PICCIOLA, G, RIVA, M, CANTARELLI, G, RAVENNA, F
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:4-alkyl-thiophenyl-ethanolamines are disclosed, which are compounds having a therapeutical activity against blood-platelet aggregation, and against lipemia and improving the cerebral circulation, said ethanolamines having the general formula: wherein R and R1 are alkyl substituents and R2 is a substituent having an amine character. Due to the presence of two asymmetry centers in their molecule, the compounds concerned can be prepared in the "threo" and the "erythro" configuration: mixtures of the "threo" and the "erythro" forms have also proven effective.