TETRAHYDRONAPHTHALENE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS

Compounds are provided having the structure wherein R and R may be the same or different and are hydrogen, lower alkyl, lower alkenyl, or hydroxy-lower alkyl, or R and R together with the nitrogen atom to which they are attached also form a heterocyclic radical which may contain another heteroatom,...

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Hauptverfasser: HAUCK F.P, FOX R.T
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds are provided having the structure wherein R and R may be the same or different and are hydrogen, lower alkyl, lower alkenyl, or hydroxy-lower alkyl, or R and R together with the nitrogen atom to which they are attached also form a heterocyclic radical which may contain another heteroatom, namely nitrogen, oxygen or sulfur; R and R may be the same or different and are hydrogen or lower alkyl. These compounds are useful in the treatment of arrhythmia. In addition novel intermediates are provided having the structure wherein R is hydrogen, benzyl or These intermediates are also useful in treating acute myocardial infarction.