Tetrahydrofuran-antifungale midler

Tetrahydrofuran-antifungale midler

A compound represented by formula (I), wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C4 to C5) alkyl group substituted by one or two amino acid ester grou ps convertible in vivo into a hydroxy group or...

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Bibliographische Detailangaben
Hauptverfasser: PIKE, RUSSEL E, WANG, HAIYAN, BENNETT, FRANK, GIRIJAVALLABHAN, VIYYOOR M, SAKSENA, ANIL K, LOVEY, RAYMOND G, GANGULY, ASHIT KUMAR, LIU, YI-TSUNG
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A compound represented by formula (I), wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C4 to C5) alkyl group substituted by one or two amino acid ester grou ps convertible in vivo into a hydroxy group or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.