Etylamidofluorener

Substituerte fluorenforbindelser med formelen (I) er aktive som melatonergiske midler: hvor X = H, halogen, OH eller OZ, Z = C1_6-alkyl; -(CH2)m-CF3(m=0-2)/ CD3; eller /~yO-alkyl ,¿O> (m'=l-3V - v-y v l °/' n = l eller 2, og R = C1_6-alkyl, C3_g-cykloalkyl, C2_4-alkenyl, halogensubstitu...

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Hauptverfasser: TAKAKI, KATHERINE S, EPPERSON, JAMES R, LEBOULLUEC, KAREN L, WATSON, BRETT T, KARAGEORGE, GEORGE N, YEVICH, JOSEPH P
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creator TAKAKI, KATHERINE S
EPPERSON, JAMES R
LEBOULLUEC, KAREN L
WATSON, BRETT T
KARAGEORGE, GEORGE N
YEVICH, JOSEPH P
description Substituerte fluorenforbindelser med formelen (I) er aktive som melatonergiske midler: hvor X = H, halogen, OH eller OZ, Z = C1_6-alkyl; -(CH2)m-CF3(m=0-2)/ CD3; eller /~yO-alkyl ,¿O> (m'=l-3V - v-y v l °/' n = l eller 2, og R = C1_6-alkyl, C3_g-cykloalkyl, C2_4-alkenyl, halogensubstituert C-^g-alkyl, eller C1_g-alkoksy- substituert C1-C6-alkyl. Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.
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Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.</description><edition>6</edition><language>nor</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19961209&amp;DB=EPODOC&amp;CC=NO&amp;NR=962233L$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19961209&amp;DB=EPODOC&amp;CC=NO&amp;NR=962233L$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAKAKI, KATHERINE S</creatorcontrib><creatorcontrib>EPPERSON, JAMES R</creatorcontrib><creatorcontrib>LEBOULLUEC, KAREN L</creatorcontrib><creatorcontrib>WATSON, BRETT T</creatorcontrib><creatorcontrib>KARAGEORGE, GEORGE N</creatorcontrib><creatorcontrib>YEVICH, JOSEPH P</creatorcontrib><title>Etylamidofluorener</title><description>Substituerte fluorenforbindelser med formelen (I) er aktive som melatonergiske midler: hvor X = H, halogen, OH eller OZ, Z = C1_6-alkyl; -(CH2)m-CF3(m=0-2)/ CD3; eller /~yO-alkyl ,¿O&gt; (m'=l-3V - v-y v l °/' n = l eller 2, og R = C1_6-alkyl, C3_g-cykloalkyl, C2_4-alkenyl, halogensubstituert C-^g-alkyl, eller C1_g-alkoksy- substituert C1-C6-alkyl. 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Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Etylamidofluorener
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