Etylamidofluorener

Substituerte fluorenforbindelser med formelen (I) er aktive som melatonergiske midler: hvor X = H, halogen, OH eller OZ, Z = C1_6-alkyl; -(CH2)m-CF3(m=0-2)/ CD3; eller /~yO-alkyl ,¿O> (m'=l-3V - v-y v l °/' n = l eller 2, og R = C1_6-alkyl, C3_g-cykloalkyl, C2_4-alkenyl, halogensubstitu...

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Bibliographische Detailangaben
Hauptverfasser:	TAKAKI, KATHERINE S, EPPERSON, JAMES R, LEBOULLUEC, KAREN L, WATSON, BRETT T, KARAGEORGE, GEORGE N, YEVICH, JOSEPH P
Format:	Patent
Sprache:	nor
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Substituerte fluorenforbindelser med formelen (I) er aktive som melatonergiske midler: hvor X = H, halogen, OH eller OZ, Z = C1_6-alkyl; -(CH2)m-CF3(m=0-2)/ CD3; eller /~yO-alkyl ,¿O> (m'=l-3V - v-y v l °/' n = l eller 2, og R = C1_6-alkyl, C3_g-cykloalkyl, C2_4-alkenyl, halogensubstituert C-^g-alkyl, eller C1_g-alkoksy- substituert C1-C6-alkyl. Novel substituted fluorene compunds of Formula I are active as melatonergic agents: wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl; -(CH2)m-CF3 (m=0-2); CD3; or n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl.