Ekspresjon av urokinase plasminogen aktivator inhibitorer

En fremgangsmåte for fremstilling av en uroklnase-type plasralnogen aktivator Inhlbltor ved uttrykning av 4g fra gjær er beskrevet. Unfucosylated huPAR polypeptides that contains huPA1-48 (SEQ ID NQ:22) are provided. These polypeptides are useful for treating diseases wherein antagonism of huPAR is...

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Hauptverfasser:	STRATTON-THOMAS, JENNIFER R, ROSENBERG, STEVEN
Format:	Patent
Sprache:	nor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	En fremgangsmåte for fremstilling av en uroklnase-type plasralnogen aktivator Inhlbltor ved uttrykning av 4g fra gjær er beskrevet. Unfucosylated huPAR polypeptides that contains huPA1-48 (SEQ ID NQ:22) are provided. These polypeptides are useful for treating diseases wherein antagonism of huPAR is therapeutically beneficial.