Syntetiske eksitatoriske aminosyrer

The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders. The compounds have the formula wherein: X is (CH2)n; R is CO2R and R is hydrogen, or R is hydrogen and R is CO2R ;...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MONN, JAMES ALLEN, ROBEY, ROGER LEWIS, SCHOEPP, DARRYLE DARWIN, TIZZANO, JOSEPH PATRICK, HELTON, DAVID REED
Format:	Patent
Sprache:	nor
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders. The compounds have the formula wherein: X is (CH2)n; R is CO2R and R is hydrogen, or R is hydrogen and R is CO2R ; R and R are independently hydrogen, C1-C10 alkyl, C2-C10 alkenyl, aryl, or arylalkyl; and n is 1; or a pharmaceutically-acceptable salt thereof. cer