(S)-(+)-hydroksyklorokin og anvendelse derav for fremstilling av legemidler

(S)-(+)-hydroksyklorokin og anvendelse derav for fremstilling av legemidler

The present invention provides (S)-(+)-Hydroxychloroquine substantially free of (R)-(-)-hydroxychloroquine, or a pharmaceutically acceptable acid-addition salt thereof, the use in the manufacture of a medicament for treatment of malaria, lupus erythematosus or rheumatoid arthritis and a composition...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MICHNE, WILLIAM FRANCIS, STECHER, VERA JOHANNA
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention provides (S)-(+)-Hydroxychloroquine substantially free of (R)-(-)-hydroxychloroquine, or a pharmaceutically acceptable acid-addition salt thereof, the use in the manufacture of a medicament for treatment of malaria, lupus erythematosus or rheumatoid arthritis and a composition containing it for the treatment of such diseases. The weight ratio of (S)-(+)-Hydroxychloroquine to (R)-(-)-hydroxychloroquine is preferably at least 90:10, most preferably at least 98:2.