NYE DERIVATER AV BENZIMIDAZOLER MED ANTI-ULCUSAKTIVITET OG FREMGANGSMAATE FOR DERES FREMSTILLING

Novel compounds of the general formula I processes for its preparation, pharmaceutical compositions containing such compounds as the active ingredient and the use of the compounds in medicine, especially for use in inhibiting gastric acid secretion and in the treatment of gastrointestinal inflammato...

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Hauptverfasser: LINDBERG, PER LENNART, BRIVING, CARIN BIRGITTA, NORDBERG, MATS PETER, MATTSSON, ANNIE HILLEVI, CARLSSON, STIG AAKE INGEMAR, WALLMARK, BJOERN MORGAN GABRIEL
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Sprache:nor
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Zusammenfassung:Novel compounds of the general formula I processes for its preparation, pharmaceutical compositions containing such compounds as the active ingredient and the use of the compounds in medicine, especially for use in inhibiting gastric acid secretion and in the treatment of gastrointestinal inflammatory deseases. R represents aryl, cycloalkyl or an adamantyl group. R represents hydrogen, alkyl, alkoxy or halogen. R represents hydrogen, alkyl, phenalkyl or a cykloalkyl-alkyl group. R and R represents hydrogen or alkyl. R represents hydrogen, alkyl, aryl or a hydroxylgroup when n= 1-6 or an amino when n=O. A representents an alkylene, optionally connected to, or interrupted by an optionally substituted heteroatom selected from O,S and NR. n is 0-6.