REKONDISJONERINGSAPPARAT

Various embodiments of an improved reconstitution device 30, 168, 170, 186, 242, 256, 274 are disclosed, directed to the proper mixing of two substances, and are particularly directed to the medical field for the reconstitution of a drug 36 which may be stored in a drug vial 32 with a diluent 60 stored in a flexible medical solution container 34 and used for the intravenous delivery of a medicament. In one embodiment the reconstitution device 30 includes an improved vial adapter 76 and bag adapter 78 which permit the permanent coupling of the vial 32 and liquid container 34. The bag adapter 78 may be rotatable relative to the vial adapter 76 to operate a valve including a stem channel 108 and a base post 148 on the vial adapter 76, a base segment channel 136 and a cut out portion 146 of a rim 140 on the bag adapter 78, and a sealing segment 80 disposed between the vial and bag adapter 76, 78. The reconstitution device 30 reduces drug waste in hospitals, eliminates the need to relabel parenteral solution containers after a drug has been added, and prevents repeated exposure of hospital personnel to various drugs.