FREMGANGSMAATE FOR FREMSTILLING AV DIPYRIDAMOL-PREPARATER MED PH-UAVHENGIG REGULERT FRIGJOERING

Novel pH independent, controlled release oral tablets comprising an effective amount of an intimate mixture of dipyridamole or an acid addition salt thereof, at least 18 acid equivalents of at least one non-toxic, pharmaceutical acid or acid substance per mole of dipyridamole and a sufficient amount...

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Bibliographische Detailangaben
Hauptverfasser: MOONEY, KIERAN G, DEBSKI, JERZY, PARK, YUNG-YONG
Format: Patent
Sprache:nor
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Zusammenfassung:Novel pH independent, controlled release oral tablets comprising an effective amount of an intimate mixture of dipyridamole or an acid addition salt thereof, at least 18 acid equivalents of at least one non-toxic, pharmaceutical acid or acid substance per mole of dipyridamole and a sufficient amount of a disintegration agent to allow at least 90% dissolution of dipyridamole in the gastrointestinal pH range of 1 to 7.