FREMGANGSMAATE FOR FREMSTILLING AV ANTRACYKLINANTIBIOTIKA MED ANTIKREFTVIRKNING OG NY MIKRO-ORGANISMESTAMME

The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 3...

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Hauptverfasser:	TAIG, MARIA M, NAVASHIN, SERGEI M, SINGAL, EMILIA M, SOIFER, VLADIMIR S, CHERNYSHEV, ALEXEI I, KLJUEV, N.A, IVANITSKAYA, LJUDMILA PETROVNA, KRJUCHKOVA, ELENA I, ESIPOV, STANISLAW E, VESELOVA, SVETLANA I, FOMINA, INESSA P, TERENTIEVA, TATYANA G
Format:	Patent
Sprache:	nor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS SPIRITS VINEGAR WINE
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Zusammenfassung:	The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 30 DEG C and at a pH of 6 - 8.5 for 48 - 96 h.