NYE DIHYDROPYRIDINER

New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of l...

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Hauptverfasser: BERNTSSON, PEDER BERNHARD, LJUNG, BENGT RICHARD, CARLSSON, STIG AAKE INGEMAR
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creator BERNTSSON, PEDER BERNHARD
LJUNG, BENGT RICHARD
CARLSSON, STIG AAKE INGEMAR
description New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of lower alkyl, NO2, CN, CF3, Cl and Br; A is a straight or branched alkylene group with 2-5 carbon atoms; R is wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R and R are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.
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A is a straight or branched alkylene group with 2-5 carbon atoms; R is wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R and R are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.</description><edition>3</edition><language>nor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; 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A is a straight or branched alkylene group with 2-5 carbon atoms; R is wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R and R are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1983</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBDxi3RVcPH0iHQJ8g-IDPJ08fRzDeJhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfF-_hbGhhYGZj4-xoRVAAAiIx5m</recordid><startdate>19831122</startdate><enddate>19831122</enddate><creator>BERNTSSON, PEDER BERNHARD</creator><creator>LJUNG, BENGT RICHARD</creator><creator>CARLSSON, STIG AAKE INGEMAR</creator><scope>EVB</scope></search><sort><creationdate>19831122</creationdate><title>NYE DIHYDROPYRIDINER</title><author>BERNTSSON, PEDER BERNHARD ; LJUNG, BENGT RICHARD ; CARLSSON, STIG AAKE INGEMAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NO831806LL3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>nor</language><creationdate>1983</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BERNTSSON, PEDER BERNHARD</creatorcontrib><creatorcontrib>LJUNG, BENGT RICHARD</creatorcontrib><creatorcontrib>CARLSSON, STIG AAKE INGEMAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BERNTSSON, PEDER BERNHARD</au><au>LJUNG, BENGT RICHARD</au><au>CARLSSON, STIG AAKE INGEMAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NYE DIHYDROPYRIDINER</title><date>1983-11-22</date><risdate>1983</risdate><abstract>New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of lower alkyl, NO2, CN, CF3, Cl and Br; A is a straight or branched alkylene group with 2-5 carbon atoms; R is wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R and R are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.</abstract><edition>3</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NYE DIHYDROPYRIDINER
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