NYE DIHYDROPYRIDINER

New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of l...

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Bibliographische Detailangaben
Hauptverfasser: BERNTSSON, PEDER BERNHARD, LJUNG, BENGT RICHARD, CARLSSON, STIG AAKE INGEMAR
Format: Patent
Sprache:nor
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Beschreibung
Zusammenfassung:New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula wherein R is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of lower alkyl, NO2, CN, CF3, Cl and Br; A is a straight or branched alkylene group with 2-5 carbon atoms; R is wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R and R are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.