2-METYL-6-SUBSTITUERTE 4-(2,3-DIKLORFENYL-1,4-DIHYDROPYRIDIN)-3,5-DIKARBOKSYLSYRE-3,5-DIESTERE MED HYPOTENSIVE EGENSKAPER, FREMGANGSMAATE FOR DERES FREMSTILLING AV FARMASOEYTISKE PREPARATER INNEHOLDENDE DISSE

2-METYL-6-SUBSTITUERTE 4-(2,3-DIKLORFENYL-1,4-DIHYDROPYRIDIN)-3,5-DIKARBOKSYLSYRE-3,5-DIESTERE MED HYPOTENSIVE EGENSKAPER, FREMGANGSMAATE FOR DERES FREMSTILLING AV FARMASOEYTISKE PREPARATER INNEHOLDENDE DISSE

The present invention relates to new compounds having anti-hypertensive effect, which compounds are of the formula I, wherein R is selected from the group consisting of -CH3, -CH2CH2OCH3, and -CH(CH3)CH2OCH3, R is selected from the group consisting of -CH3, -C2H5, -CH2CH2OCH3, and -CH(CH3)CH2OCH3, w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BERNTSSON, PEDER BERNHARD, LJUNG, BENGT RICHARD, GAARDER, JAN OERNULF, CARLSSON, STIG AAKE INGEMAR
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to new compounds having anti-hypertensive effect, which compounds are of the formula I, wherein R is selected from the group consisting of -CH3, -CH2CH2OCH3, and -CH(CH3)CH2OCH3, R is selected from the group consisting of -CH3, -C2H5, -CH2CH2OCH3, and -CH(CH3)CH2OCH3, whereby when R is -CH3, R is -CH3, -C2H5, -CH2CH2OCH3, or -CH(CH3)CH2OCH3, when R is -CH2CH2OCH3, R is -CH2CH2OCH3, or -CH(CH3)CH2OCH3, and when R is -CH(CH3)CH2OCH3, R is -CH(CH3)CH2OCH3, and R is selected from the group consisting of alkyl with 2 to 3 C, alkoxyalkyl with 2 to 3 C, and alkoxyalkoxyalkyl with 3 to 5 C, process for the preparation of said compounds, pharmaceutical preparations containing said compounds.