MEMBRANSTABILISERENDE FORBINDELSER SOM HAR BETA-RECEPTOR BLOKKERENDE AKTIVITET, DERES FREMGANGSMAATE SAMT FREMGANGSMAATE FOR BEHANDLING AV ARRHYTMETISKE TILSTANDER, OG FARMASOEYTISKE PREPARATER SOM INNEHOLDER DISSE

The present invention relates to new potent membrane stabilizing compounds of the formula wherein R is alkoxyalkyl, hydroxyalkyl or alkyl, which alkyl groups may be branched or straight, R is halogen or hydrogen, R is hydrogen or alkyl, R and R are same or different and are each hydrogen, alkoxy, alkyl, alkoxyalkyl, cyano, or hydroxy, n is 0, 1, 2, or 3, and X is -O-, -CH2-, or @ The present compounds are potent heart antiarrhythmic agents possessing membrane stabilizing effect and beta -receptor blocking effect in same clinical doses. The compounds are used in treating antiarrhythmic conditions, but can also be used in the treatment of hypertension, angina pectoris, or nervous heart. The invention also relates to processes for preparing the compounds, method of treating antiarrhythmic conditions and pharmaceutical preparations containing said compounds.