FREMGANGSMAATE VED FREMSTILLING AV 1-AZIRIDIN-CARBOXYLSYREESTER-DERIVATER

FREMGANGSMAATE VED FREMSTILLING AV 1-AZIRIDIN-CARBOXYLSYREESTER-DERIVATER

An aziridine derivative of the formula II is reacted with a haloformic ester of the formula III, in which Hal denotes chlorine or bromine, e.g. in an inert solvent. 1-Aziridinecarboxylic ester derivatives of the formula I are obtained, in which X and R have the meaning listed in Claim 1. The compoun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HEERDT, RUTH, BOSIES, ELMAR, GALL, RUDI, BICKER, UWE, ZIEGLER, ANNA ELISABETH
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:An aziridine derivative of the formula II is reacted with a haloformic ester of the formula III, in which Hal denotes chlorine or bromine, e.g. in an inert solvent. 1-Aziridinecarboxylic ester derivatives of the formula I are obtained, in which X and R have the meaning listed in Claim 1. The compounds of the formula I possess, for example, a pronounced immunostimulatory effect.