Fremgangsmåte for fremstilling av en tablett for oral administrering av ibuprofen, dexibuprofen (S(+)-ibuprofen) eller en blanding derav

A fused solid dispersion comprising an active ingredient having a melting point of 800 C or below and a pharmaceutically acceptable absorbent having a specific surface area ranging from 20 to 400 mVg can be conveniently compressed into a tablet without generating capping and sticking problems, and a...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Sang Wook, Ryu, Jae Kuk, Woo, Jong-Soo, Yi, Hong Gi
Format: Patent
Sprache:nor
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Zusammenfassung:A fused solid dispersion comprising an active ingredient having a melting point of 800 C or below and a pharmaceutically acceptable absorbent having a specific surface area ranging from 20 to 400 mVg can be conveniently compressed into a tablet without generating capping and sticking problems, and a tablet comprising said fused solid dispersion can maintain an uniform release rate over a prolonged time when orally administered.