Forbindelser med HIV-proteaseaktivitet, farmasøytisk preparat derav og anvendelse derav ved fremstillingen av et medikament for behandling eller forebyggelse av symptomene eller virkningene av HIV-infeksjon

Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as...

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Hauptverfasser:	YU RICHARD H, DASTGAH AZAR, ZHANG JIANCUM, YANG ZHENG-YU, LEE WILLIAM A, ARIMILLI MURTY N, XU LIANHONG, CHEN JAMES M, TARIO JAMES D, BRYANT CLIFFORD M, PYUN HYUNG-JUNG, MACKMAN RICHARD L, HE GONG-XIN, WANG JIANYING, FARDIS MARIA, SWAMINATHAN SUNDARAMOORTHI, BECKER MARK M, WILLIAMS MATTHEW A, NELSON PETER HAROLD, LIU HONGTAO, MITCHELL MICHAEL L, JIN HAOLUN, ZHANG LIJUN, LIN KUEI-YING, KIM CHOUNG U, CHEN XIAOWU, ROWE TANISHA D, LEE CHRISTOPHER P, SPARACINO MARK L
Format:	Patent
Sprache:	nor
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.