4,5-diaryl-3(2H)-furanonderivater, fremgangsmate for fremstilling derav, farmasoytiske preparater samt anvendelse av slike derivater

The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.

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Bibliographische Detailangaben
Hauptverfasser:	LIM KYUNG MIN, MOH JOO HYUN, CHUNG SHIN, LEE CHANG HOON, YL JUNG BUM, SHIN SONG SEOK, CHOI YOUNG HOON, HA JUN-YONG, PARK YOUNG-HO, JOO YUNG HYUP, KIM JI YOUNG, JEONG YEON SU, BYUN YOUNG JOO, KANG SEON HWA, LEE KI-WHA, NOH MIN-SOO, KIM JIN KWAN, CHOI JIN KYU
Format:	Patent
Sprache:	nor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.