Piperidinforbindelse, farmasoytiske preparater, anvendelse av forbindelsene samt fremgangsmate for fremstilling derav

Compounds of formula (I) in free or salt form, where Ar is phenyl substituted by one or more halogen atoms, Ar is phenyl or naphthyl which is unsubstituted or substituted by one or more substituents selected from halogen, cyano, hydroxy, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkoxy or C1-C8-alkoxycarbonyl, R is hydrogen or C1-C8-alkyl optionally substituted by hydroxy, C1-C8-alkoxy, acyloxy, N(R )R , halogen, carboxy, C1-C8-alkoxycarbonyl, -CON(R )R or by a monovalent cyclic organic group, R and R are each independently hydrogen or C1-C8-alkyl, or R is hydrogen and R is acyl or -SO2R , or R and R together with the nitrogen atom to which they are attached denote a 5 or 6-membered heterocyclic group, R and R are each independently hydrogen or C1-C8-alkyl, or R and R together with the nitrogen atom to which they are attached denote a 5 or 6-membered heterocyclic group, R is C1-C8-alkyl, C1-C8-haloalkyl, or phenyl optionally substituted by C1-C8-alkyl, and n is 1, 2, 3, or 4, with the proviso that when Ar is p-chlorophenyl and R is hydrogen, R is not phenyl or p-nitrophenyl. The compounds are useful as pharmaceuticals.