Fremgangsmate til fremstilling av et 3(2H)-pyridazinon-4-substituert amino-5-klorderivat

Fremgangsmate til fremstilling av et 3(2H)-pyridazinon-4-substituert amino-5-klorderivat

The invention relates to novel processes for the preparation of 5-chloro-4-{3-[N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamino]-propylamino-3(2H) pyridazinone of formula (I) and the pharmaceutically acceptable acid addition salts thereof. An important feature of the invention is using 3,4,5-trichlor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GREFF ZOLTAN, KARNCSI TAMAS, NAGY PETER KOTAY, RATKAI ZOLTAN, SERES PETER, BARKOCZY JOZSEF, BALAZS LASZLO, SIMIG GYULA, DOMAN IMRE, SZTRUHAR ILONA
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to novel processes for the preparation of 5-chloro-4-{3-[N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamino]-propylamino-3(2H) pyridazinone of formula (I) and the pharmaceutically acceptable acid addition salts thereof. An important feature of the invention is using 3,4,5-trichloropyridazone as starting substance of the synthesis.