1-[(1-substituerte-4-piperidinyl)metyl]-4-piperidinderivater, fremgangsmater for fremstilling av disse, medisinske preparater inneholdende disse, og mellomprodukter for disse forbindelser

1-[(1-substituerte-4-piperidinyl)metyl]-4-piperidinderivater, fremgangsmater for fremstilling av disse, medisinske preparater inneholdende disse, og mellomprodukter for disse forbindelser

Compounds represented by general formula (I) or physiologically acceptable acid addition salts thereof and medicinal compositions containing these compounds as the active ingredient, wherein Ar represents (Ar-1) or (Ar-2); and A represents -Z-N(Q )(Q ), -CO-R or - (CH2)p-CH(R )-COR . Because of exhi...

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Bibliographische Detailangaben
Hauptverfasser: MORIKAGE KAZUO, HARADA HIROSHI, TATEISHI HIROTAKA, TOYOTOMI YOSHIHITO, MORIKAGE YUKIKO, KATO SHIRO, YOSHIDA NAOYUKI
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds represented by general formula (I) or physiologically acceptable acid addition salts thereof and medicinal compositions containing these compounds as the active ingredient, wherein Ar represents (Ar-1) or (Ar-2); and A represents -Z-N(Q )(Q ), -CO-R or - (CH2)p-CH(R )-COR . Because of exhibiting strong affinity for 5-HT4 receptor, these compounds are useful as drugs for accelerating the peristalsis or drugs for improving digestive tract functions.