Aza-antracyklinonderivater, fremgangsmate for fremstilling derav, anvendelse av forbindelsene samt farmasoytisk preparat

PCT No. PCT/EP96/03237 Sec. 371 Date Feb. 9, 1998 Sec. 102(e) Date Feb. 9, 1998 PCT Filed Jul. 23, 1996 PCT Pub. No. WO97/06165 PCT Pub. Date Feb. 20, 1997Compounds of formula I wherein X1 and X2 are C=O, C=NH or CH2, X3 is CH2, CO, CHOH, wherein n=2 or, 3 or C=N(R9) wherein R9 is hydroxy or amino-a...

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Bibliographische Detailangaben
Hauptverfasser:	FIARDI DANIELA, CARUSO MICHELE, SUARATO ANTONINO, LANSEN JACQUELINE, BANDIERA TIZIANO
Format:	Patent
Sprache:	nor
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Zusammenfassung:	PCT No. PCT/EP96/03237 Sec. 371 Date Feb. 9, 1998 Sec. 102(e) Date Feb. 9, 1998 PCT Filed Jul. 23, 1996 PCT Pub. No. WO97/06165 PCT Pub. Date Feb. 20, 1997Compounds of formula I wherein X1 and X2 are C=O, C=NH or CH2, X3 is CH2, CO, CHOH, wherein n=2 or, 3 or C=N(R9) wherein R9 is hydroxy or amino-aryl, and each of R1, R2, R3, R4, R5, R6, R7 and R8 are hydrogen, halogen or an organic residue, are useful in the treatment of amyloidosis. A process for their preparation and pharmaceutical compositions containing them are also described.